Chronic vein diseases and peripheral arterial diseases may cause lower leg ulceration. Accurate diagnostics is the key to successful treatment. Typical clinical manifestations of different origins’ ulcers, combined with the signs of the main disease, facilitate diagnosis.

This article attempts to summarise the problems of providing prosthetic and orthopedic care to patients with an existing manifestation of diabetic pathology of the lower extremities. In order to justify the relevance of the topic, the author studied the dynamics of amputations carried out on the territory of the Russian Federation. The organizational issues, as well as the legal problems of the primary prosthetics of patients with a diabetes diagnosis with amputation of the lower extremities are being identified. Special attention is being paid to the difficulties regarding the medical-technical nature in the case of prosthetics for patients of this category who have stump defects that impede the achievement of rehabilitation and social adaptation goals. Based on the analysis, the article concludes that it is necessary to develop a comprehensive interdisciplinary approach to the provision of medical care to such patients and rehabilitation measures.

This article deals with the application of the method of postoperative complex treatment of necrotic complications of diabetic foot syndrome in 68 patients. A feature of this method is the addition to the basic treatment of oral thrombolytic, angioprotector and venotonic. And well as postoperative local treatment of foot wounds using vacuum aspiration in two stages. The authors describe in detail the main points of this method of complex treatment and the technique of performing the stages of vacuum aspiration. And also provides a comparative analysis of the results of treatment of these patients.

This article deals with the modern complex approach to the treatment of trophic ulcers of the lower extremities of venous etiology on the example of 86 patients. Which is to add to the basic therapy of oral fibrinolytic and angioprotector. And for the local treatment of venous ulcers, bioplastic material is used. The authors describe in detail the main points of this method of complex treatment. And also provide an analysis of the results of treatment of these patients in comparison with standard basic therapy.

The results of treatment of 123 patients with performed angioplasty of arteries of the type B and C infraringinal segment (TASCII) are presented. Cylinders without drug coating were used, stent implantation was not performed. The main (group 1) — 63 patients with critical lower limb ischemia, the control (group 2) — 60 patients with intermittent claudication. Long-term results were evaluated in 59 (47.9%) periods ranging from 6 to 42 months (average 24.3±9.4 months). The patency of reconstructed arteries, the frequency of restenoses, amputations in the period from 6 to 42 months were evaluated: 20 (57.1%), 5 (14.3%), 3 (8.6%) in the main group and 13 (54.2%), 9 (37.5%), 1 (4.2%) in the control. Mortality among patients with critical ischemia was 7 (20%), in patients with grade IIB ischemia — 1 (4.2%). The revealed differences between the groups when studying outcomes in the long-term period were statistically unreliable (p>0.05). This issue requires further study and even more careful attitude to decision-making on the need and method of limb revascularization in patients with a clinic of intermittent claudication.

The paper presents a method for assessing surgical risks in carotid endarterectomy. Complications in the immediate postoperative period were covered in detail: ischemic and hemorrhagic strokes, transient ischemic attacks, myocardial infarction, subarachnoid hemorrhage, postoperative occlusion of the internal carotid artery, cerebral hyperperfusion syndrome, damage to cranial nerves, postoperative neck hematoma, hoarseness of voice, malignant arterial hypertension. Attention is also focused on restenosis in the remote operational period. The conditions under which it is possible to minimize the risk of complications during this surgery are noted.

Hybrid interventions are one of the novel methods to treat critical limb ischemia and, therefore, lack scientific evidence. Published data are usually scanty, originating from a single center and rarely exceeding one hundred cases. No randomized and virtually no large comparative studies of hybrid versus conventional open reconstructions have been published. It is still unclear which patients with combined iliac and infrainguinal disease might benefit from a hybrid intervention, how the outcome is affected by the lesion type and the degree of ischemia and is it possible to improve the result by using more sophisticated devices, such as stent-grafts, drug-coated balloons and scaffolds.

Until nowadays, there are no common understanding of causes, inner nature and general concept of schizophrenia. The author`s theory of schizophrenia as a process of formation of specific emotional-volitional defect, which is a form of adaptive functioning of mentality as pathology was observed in the article. The clinical types and severity of emotional-volitional defect, its dynamic, which are necessary in medical and social expertise and judicial-psychiatric practice, were obtained in the article. The criterion of schizophrenia progression was offered.