Purpose: to justify the need to use the preventive dose indicator to increase the effectiveness of activities carried out in programs and national projects to improve health, reduce mortality and increase active life expectancy. The concept of «preventive dose» is recommended to be used in the practical and scientific activities of specialists in the public health system and clinical medicine. This approach is of particular importance in terms of the development of the doctrine of polypathy and its prevention among adults, children and adolescents.

The urgency. Treatment of the restrained hernias of a forward belly wall remains a serious problem modern emergency to surgery that is caused high mortalities — in Russia, agrees to data of different authors, it makes from 2 to 9.5%, and the number of relapses after plastic of hernial gate local fabrics reaches level of 33%. The question by definition of indications to use of mesh materials and their kinds for liquidation of hernial defect is not solved up to the end, especially at a resection of a loop of intestines in urgent situations.
Goal: to improve the treatment results of patients with anterior abdominal wall hernias have been infringed.
Material and methods. The analysis of direct results of treatment of 431 patients with the restrained hernias of a forward belly wall at which is presented used technology with application using a Prolene mesh.
Results. Patients with restrained groin hernias was 146 (32.3%), with umbilical — 143 (31.5%), postoperative ventral hernias — 85 (18.9%), a white line of a stomach — 34 (7.5%), femoral — 30 (6.8%) and other localisations 13 sick (3%). After 24 hours from the disease beginning 108 patients (24%) have addressed. Necrosis guts at its infringement in the hernial collars, demanded its resection were at 44 patients (9.6%). Postoperative complications are noted at 72 patients (15.8%). Arose seroms in a zone of implantation of a grid — at 56 patients (12.4%) More often, wound suppurations are noted at 12 (2.7%), the postoperative pneumonia was at 4 sick (0.7%). Has died after operation of 9 persons (1.9%).
The conclusion. The discussed technique of treatment is enough safe, economic technology and conducts to improvement of direct results of treatment.

The article presents the causal relationships of bloodstream infection in the medical organization of the city of Chelyabinsk. A retrospective analysis of the dynamics of 4 years (2015–2018) of cases of bloodstream infection in intensive care units, cardiology, toxicology, gastroenterology, therapy, surgery, urology was carried out. As a result of the presented analysis, it was revealed that bloodstream infections make up 6.5% of all cases of infections associated with medical care. The greatest number of cases of bloodstream infection was noted in intensive care units, which is associated with not timely, not high-quality treatment of the injection field and venous catheter by medical personnel. As a result of complex etiological and epidemiological analyses of cases of bloodstream infection, recommendations for prevention and prevention of its development, improvement of control and Supervisory measures were developed.

The purpose of the study is to study the organization of clinical examination and follow-up observation in the conditions of the central district hospital and to develop measures for improvement. The basis of the study was the polyclinic of the municipal institution «Krasnoarmeisk regional hospital». Analyzed the accounting reports on clinical examination and follow-up of patients. According to a specially designed questionnaire, a continuous method was used to interview doctors and selectively — patients. Objective reasons for the unsatisfactory organization of clinical examination and follow-up observation: the discrepancy between the requirements of regulatory documents on clinical examination and the capabilities of the medical organization due to insufficient staffing and the necessary equipment. Subjective reasons: the lack of methodological materials on the analysis of the effectiveness of clinical examination, the indifferent attitude of the doctors themselves to the clinical examination, the incompetence of the doctors in the analysis of clinical follow-up, low motivation of citizens, lack of information about the goals and objectives of the clinical examination. Proposed measures to optimize this section of work.

From glaucoma every year 10 million people completely lose vision, one of the factors of which is untimely diagnosis. Donosological diagnosis and laboratory screening can play a key role in detecting this pathology and significantly improving the quality of life of the older generation. The article presents the results of comparative analysis of the general blood analysis of glaucoma patients by sex.

The mechanisms of the formation of cardiopathy in the treatment of anticancer drugs, its forms and the place of functional research methods in the diagnosis of heart damage in cancer patients are presented.

Abstract. This article discusses the activities of the outstanding doctor Leo Antonovich Bokeria as a cardiac surgeon, teacher and public figure. The contribution to the development of domestic science and cardiac surgery is analyzed.

The article proposes a model of neurosis, as an adaptation disease, with a violation of all basic levels of regulation of the body's activity — psychosomatic, neuropsychic and psychosocial, the causes and pathogenesis mechanisms of its formation are traced. The role of soil in the clinical presentation of neurosis is noted. The group of psychosomatic diseases in the structure of neurosis is distinguished. Ways of treatment are proposed.