Morphological features of placenta accreta spectrum
Abstract
The aim of the study: to study the histology of the placenta in its presentation and accreta. Materials and methods. A morphological study of the placenta of women who gave birth in the obstetric hospital of the Clinic of the South-Urals State Medical University in Chelyabinsk was carried out (sample size 53 preparations): group 1 — 21 preparations of normally located placenta; group 2 — 17 preparations of placenta previa without signs of placenta accreta spectrum (PAS); group 3 — 15 PAS preparations (7 cases of placenta accreta, 5 — placenta increta, 3 — placenta percreta, invasion degree 3a). For histological examination, the obtained tissue fragments were fixed in formalin solution, embedded in paraffin, plane-parallel sections were made from the paraffin blocks, stained with hematoxylin and eosin, with subsequent viewing and photography of micropreparations. Results and conclusions. Morphological examination of PAS preparations at the site of germination revealed significant thinning of the uterine wall due to aplasia or pronounced hypoplasia of the spongy and basal layers of the endometrium, the absence of a fibrinoid layer in the basal plate zone, and replacement of the myometrium with connective tissue. Wide spurs of the basal plate were recorded, deeply penetrating between the terminal villi of the placenta, many of which penetrated the entire thickness of the myometrium.
About the Authors
E. G. Syundyukova
South-Urals State Medical University ; Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
S. L. Sashenkov
South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
Yu. S. Chulanova
Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
E. S. Golovneva
South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
T. V. Uzlova
South-Urals State Medical University ; Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
B. I. Medvedev
South-Urals State Medical University ; Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
N. A. Filippova
South-Urals State Medical University ; Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
Yu. A. Yakovleva
South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
L. B. Tarasova
South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
M. S. Kirsanov
Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
N. M. Diner
Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
E. Yu. Kotlyarova
Clinic of the South-Urals State Medical University
Russian Federation
Russian Federation
Chelyabinsk
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Review
For citations:
Syundyukova E.G., Sashenkov S.L., Chulanova Yu.S., Golovneva E.S., Uzlova T.V., Medvedev B.I., Filippova N.A., Yakovleva Yu.A., Tarasova L.B., Kirsanov M.S., Diner N.M., Kotlyarova E.Yu. Morphological features of placenta accreta spectrum. Title in english. 2025;20(3):8-11. (In Russ.)
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