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Refractory iron deficiency anemia in a patient with GAVE-syndrome

Abstract

   The aim: to consider aspects of detection and treatment of patients with GAVE syndrome.

   Materials and methods. The article is devoted to the correction of iron deficiency in ectasia of the vessels of the antrum. Theories of pathogenesis, endoscopic picture and clinical case of a patient with GAVE syndrome are described.

   Results and conclusions. Gastric antral vascular ectasia (GAVE) is a rare but clinically important cause of chronic gastrointestinal bleeding. The etiology of GAVE syndrome is not fully understood and remains controversial. The diagnosis is based on the endoscopic picture, which is characterized by bright areas of hyperemia in the form of stripes radiating from the pylorus to the antrum and resembling a watermelon. The clinical picture can vary from iron deficiency anemia, hidden blood loss, melena to hematemesis. Therapy is limited to a surgical or endoscopic approach, as most medical treatments have shown inconsistent results. Here, we review the efficacy of these treatment options and methods for identifying patients with GAVE syndrome.

About the Authors

G. E. Zalova
South-Urals State Medical University
Russian Federation

Chelyabinsk



O. V. Korobitsyna
South-Urals State Medical University
Russian Federation

Chelyabinsk



References

1. Rider, J. A. Gastritis with veno-capillary ectasia as a source of massive gastric hemorrhage / J. A. Rider, A. P. Klotz, J. B. Kirsner // Gastroenterology. – 1953. – Т. 24, № 1. – С. 118–123.

2. Jabbari, M. Gastric antral vascular ectasia: the watermelon stomach / M. Jabbari, R. Cherry, J. O. Lough [et al.] // Gastroenterology. – 1984. – Т. 87, № 5. – С. 1165–1170.

3. Fuccio L. Diagnosis and management of gastric antral vascular ectasia / L. Fuccio, A. Mussetto, L. Laterza, L. H. Eusebi, F. Bazzoli. – World J. Gastrointest. Endosc. – 2013. – Т. 5, № 1. – C. 6–13.


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For citations:


Zalova G.E., Korobitsyna O.V. Refractory iron deficiency anemia in a patient with GAVE-syndrome. Title in english. 2023;18(2):28-31. (In Russ.)

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ISSN 2949-6292 (Print)